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Genomic imbalances in the placenta are associated with poor fetal growth.

Giulia F Del GobboYue YinSanaa ChoufaniEmma A ButcherJohn WeiEvica Rajcan-SeparovicHayley BosPeter von DadelszenRosanna WeksbergWendy P RobinsonRyan K C Yuen
Published in: Molecular medicine (Cambridge, Mass.) (2021)
We conclude that placental genomic imbalances at the cytogenetic and submicroscopic level may underlie up to ~ 18% of SGA cases in our population. This work contributes to the understanding of the underlying causes of placental insufficiency and FGR, which is important for counselling and prediction of long term outcomes for affected cases.
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