Direct electrical stimulation impacts on neuromuscular junction morphology on both stimulated and unstimulated contralateral soleus.
Young Il LeeNicola CaccianiYa WenXiang ZhangYvette HedströmWesley ThompsonLars LarssonPublished in: Journal of cachexia, sarcopenia and muscle (2023)
Motor axon terminals and terminal Schwann cells at NMJs of rats subjected to post-synaptic neuromuscular blockade exhibited sprouting responses. These axonal and glial responses were likely dampened by a muscle-derived myokines released in an activity-dependent manner with both local and systemic effects.