Login / Signup

Effects of liquid extract from Plinia cauliflora fruits residues on Chinese hamsters biochemical parameters.

Leonardo Luiz BorgesFrederico Severino MartinsJoão José FrancoElisa Flávia Luiz Cardoso BailãoWilson de Melo CruvinelSérgio Akira UyemuraEdemilson Cardoso da Conceição
Published in: Brazilian journal of biology = Revista brasleira de biologia (2021)
Plinia cauliflora (Mart.) Kausel, popularly known as jabuticaba, is rich in polyphenols. Phenolic compounds exhibit several biological properties, which reflect on biomarkers such as biochemical parameters. In the present study, we evaluated the plasmatic levels of glucose, total cholesterol, HDL-cholesterol, triglycerides, and uric acid of Chinese hamsters fed for 45 days with a regular diet or cholesterol-enriched diet supplemented with a liquid extract obtained from P. cauliflora fruits residues standardized in ellagic acid and total phenolic compounds. The results showed that the concentrated extract obtained from jabuticaba residues increased the glycemia of animals fed with a regular diet and reduced the plasmatic uric acid levels of animals fed with a cholesterol-enriched diet. Since hyperuricemia is considered to be a significant risk factor of metabolic disorders and the principal pathological basis of gout, the liquid extract from P. cauliflora fruits residues would be a promising candidate as a novel hypouricaemic agent for further investigation.
Keyphrases
  • uric acid
  • metabolic syndrome
  • low density lipoprotein
  • weight loss
  • physical activity
  • oxidative stress
  • ionic liquid
  • risk factors
  • insulin resistance
  • blood pressure