The diagnostic accuracy of Raman spectroscopy integrated with polarized light microscopy for calcium pyrophosphate associated arthritis.

Tom NiessinkMatthijs JanssenTanja GiesenMonique N EfdéAntoaneta C ComarniceanuCees OttoTim L Jansen

Published in: Arthritis care & research (2024)

iRPolM can easily identify CPP crystals with a strong diagnostic performance. PLM alone is not specific enough to reliably resolve complicated cases and the implementation of Raman spectroscopy in rheumatology practice can be of benefit to patients with suspected CPPD.

Keyphrases

raman spectroscopy
primary care
healthcare
quality improvement
rheumatoid arthritis
single molecule
high resolution
high throughput
high speed
juvenile idiopathic arthritis
room temperature
disease activity
ionic liquid