Exploring the clinical utility of two staging models for bipolar disorder.
Afra van der MarktUrsula M H KlumpersAnnemieke DolsStasja DraismaMarco P M BoksAnnet van BergenRoel A OphoffAartjan T F BeekmanRalph W KupkaPublished in: Bipolar disorders (2019)
The majority of patients with BD-I clustered in recurrent stage 3 of Model A. Model B showed a larger dispersion. The stepwise change in several clinical markers supports the construct validity of both models. Combining the two staging models and sub-differentiating the recurrent stage into categories with cut-offs at 5 and 10 lifetime episodes improves the clinical utility of staging for individual patients.