Assessing the consistency of iPSC and animal models in cystic fibrosis modelling: A meta-analysis.

Toqa DarwishAzhar Al-KhulaifiMenatalla AliRana MowafyAbdelilah ArredouaniSuhail A DoiMohamed M Emara

Published in: PloS one (2022)

Studies on both animal and iPSCs models generated considerable heterogeneity. Given the potential of iPSC-derived models to study different diseases, we recommend paying more attention to developing reproducible models of iPSC as it has potential if adequately developed.

Keyphrases

induced pluripotent stem cells
cystic fibrosis
working memory
single cell
risk assessment
chronic obstructive pulmonary disease
case control