CRP under 130 mg/L rules out the diagnosis of Legionella pneumophila serogroup 1 (URINELLA Study).

Timothée KlopfensteinSouheil ZayetSamantha PoloniVincent GendrinDamien FournierJean-Baptiste VuillemenotPhilippe SellesAlain DussaucyGaelle CoureauMarta Avalos-FernandezLynda TokoPierre-Yves RoyerCharles-Eric LavoignetBouchra AmariMarc PuyraveauCatherine Chirouze

Published in: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology (2024)

In case of pneumonia suspicion with a CRP level under 130 mg/L (independently of the severity) L-UAT is useless in immunocompetent patients with a NPV at 100%. We must remain cautious in patients with symptoms onset less than 48 h before CRP dosage.

Keyphrases

physical activity
depressive symptoms
acute respiratory distress syndrome
community acquired pneumonia
mechanical ventilation