Humoral immune response to COVID-19 vaccination in diabetes is age-dependent but independent of type of diabetes and glycaemic control: The prospective COVAC-DM cohort study.

Caren SourijNorbert J TripoltFaisal AzizFelix AbererPatrick ForstnerAnna M ObermayerHarald KojzarBarbara KleinhapplPeter N PferschyJulia K MaderGerhard CvirnNandu GoswamiNadine WachsmuthMax L EcksteinAlexander MüllerFarah AbbasJacqueline LenzMichaela SteinbergerLisa KnollRobert KrauseMartin StradnerPeter SchlenkeNazanin SarebanBarbara PrietlSusanne KaserOthmar MoserIvo SteinmetzHarald Sourijnull null

Published in: Diabetes, obesity & metabolism (2022)

Anti-SARS-CoV-2 S receptor-binding domain antibody levels after the second vaccination were comparable in healthy controls and in participants with type 1 and type 2 diabetes, irrespective of glycaemic control. Age and renal function correlated significantly with the extent of antibody levels.

Keyphrases

type diabetes
sars cov
immune response
glycemic control
cardiovascular disease
respiratory syndrome coronavirus
coronavirus disease
insulin resistance
dendritic cells
binding protein
dna binding