Human granulosa cells of poor ovarian responder patients display telomeres shortening.

Yuval YungSharon Avhar MaydanYossi BartRaoul OrvietoAdva Aizer

Published in: Journal of assisted reproduction and genetics (2023)

Granulosa cells telomere length of the young normal responder was found to be significantly longer than young poor ovarian responder or elderly patients, highlighting the role of telomere length as a predictor, or contributor to poor oocyte yield following IVF treatment.

Keyphrases

induced apoptosis
cell cycle arrest
end stage renal disease
endothelial cells
ejection fraction
newly diagnosed
polycystic ovary syndrome
type diabetes
prognostic factors
cell death
signaling pathway
oxidative stress
pregnant women
adipose tissue
skeletal muscle
combination therapy