Effect of Triglyceride-Glucose Indices and Circulating PCSK9-Associated Cardiovascular Risk in STEMI Patients with Primary Percutaneous Coronary Artery Disease: A Prospective Cohort Study.
Xiaoxiao ZhaoLi SongJiannan LiJinying ZhouNan LiShaodi YanRunzhen ChenYing WangChen LiuPeng ZhouZhaoxue ShengYi ChenHanjun ZhaoHong-Bing YanPublished in: Journal of inflammation research (2023)
Elevated PCSK9 levels are related to all-cause mortality and cardiac-related mortality when TyG levels are greater than the median, but not when levels are less than the median. This suggests a potential benefit of lowering circulating PCSK9 levels in STEMI patients with insulin resistance.
Keyphrases
- coronary artery disease
- insulin resistance
- percutaneous coronary intervention
- cardiovascular events
- type diabetes
- heart failure
- cardiovascular disease
- low density lipoprotein
- high fat diet
- risk factors
- risk assessment
- blood pressure
- polycystic ovary syndrome
- drug induced
- atrial fibrillation
- aortic valve
- glycemic control
- weight loss
- high fat diet induced