Altered polarization and impaired phagocytic activity of lung macrophages in people with HIV and COPD.
Kentaro AkataJanice M LeungKei YamasakiFernando S Leitao FilhoJulia YangChen Xi YangHiroto TakiguchiTawimas ShaipanichBasak SahinBeth A WhalenCheng Wei Tony YangDon D SinStephan F van EedenPublished in: The Journal of infectious diseases (2021)
PWH with COPD have an abundance of non-polarized macrophages which have poor phagocytic capacity therefore predispose them to increased risk of disease progression.