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Barbigerone Potentially Alleviates Rotenone-Activated Parkinson's Disease in a Rodent Model by Reducing Oxidative Stress and Neuroinflammatory Cytokines.

Khalid M AlharthyHassan N AlthurwiFaisal F AlbaqamiAli I AltharawiSami I AlzareaFahad A Al-AbbasiMuhammad Shahid NadeemImran Kazmi
Published in: ACS omega (2023)
The results demonstrated that barbigerone exhibits antioxidant and anti-inflammatory actions via reducing oxidative stress and inflammatory cytokines. Altogether, these findings suggest that barbigerone could potentially be utilized as a therapeutic agent against PD.
Keyphrases
  • oxidative stress
  • anti inflammatory
  • diabetic rats
  • dna damage
  • ischemia reperfusion injury
  • induced apoptosis
  • heat shock
  • heat stress