Comparison of before versus after intravitreal bevacizumab injection, growth factor levels and fibrotic markers in vitreous samples from patients with proliferative diabetic retinopathy.

Fevzi Ozer Ecem Önder Tokuç Merve Gulsen Bal Albayrak Gurler Akpinar Murat Kasap Veysel Levent Karabas

Published in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2022)

The levels of VEGF and other cytokines changed in the vitreous after IVB. The adverse effects associated with IVB, such as fibrosis, may result from modulation of vitreous cytokine concentrations. In the treatment of PDR, drugs that optimize the effects of PIGF, IGF-1, and VE-cadherin to reduce these side effects may be useful.

Keyphrases

diabetic retinopathy
growth factor
optical coherence tomography
vascular endothelial growth factor
endothelial cells
systemic sclerosis
ultrasound guided
idiopathic pulmonary fibrosis
pi k akt
binding protein
combination therapy
metastatic colorectal cancer
liver fibrosis