Olfactory-cognitive index distinguishes involvement of frontal lobe shrinkage, as in sarcopenia from shrinkage of medial temporal areas, and global brain, as in Kihon Checklist frailty/dependence, in older adults with progression of normal cognition to Alzheimer's disease.
Osamu IritaniTazuo OkunoTakaki MiwaHyuma MakizakoFumino OkutaniTetsuo KashibayashiKumiko SuzukiHideo HaraEri MoriShusaku OmotoHirokazu SuzukiMinori ShibataHiroaki AdachiKenji KondoYumi Umeda-KameyamaKumie KoderaShigeto MorimotoPublished in: Geriatrics & gerontology international (2021)
Olfactory-cognitive index (|a/b|) might be a useful tool to distinguish involvement of frontal lobe shrinkage, as in sarcopenia from shrinkage of the medial temporal areas, and global brain, as in frailty/dependence, in older adults with progression of normal cognition to Alzheimer's disease. Geriatr Gerontol Int 2021; ••: ••-••.