[Pediatric keratocystic odontogenic tumor and nevoid basal cell carcinoma syndrome. Predictive factors for recurrence and aggressiveness].

N KadlubM-E GatibelzaN El HoumamiA Coulomb-LhermineV DescroixB Ruhin-PoncetN SoufirM-P VazquezA BerdalA Picard

Published in: Revue de stomatologie et de chirurgie maxillo-faciale (2012)

KOT develop in the first 10 years, in patients presenting with NBCCS, and recurrence is observed in the second and third decade. KOT are typically aggressive and have a tendency to recur, especially in patients with NBCCS. Anatomopathological examination may be predictive of the lesion's aggressiveness. Understanding the genetic and immunological mechanisms should open the way for new medical treatment.

Keyphrases

basal cell carcinoma
free survival
healthcare
minimally invasive
genome wide
copy number
gene expression
young adults
replacement therapy