Potential prediction of formulation performance in paediatric patients using biopharmaceutical tools and simulation of clinically relevant administration scenarios of nifedipine and lorazepam.

Anna C Van der VossenLidwien M HanffArnold G VultoNikoletta Fotaki

Published in: British journal of clinical pharmacology (2019)

The in vitro results obtained from these studies reveal the potential of biorelevant solubility and dissolution studies reflecting clinical practice to predict drug performance in paediatric patients.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
emergency department
clinical practice
prognostic factors
drug delivery
gene expression
risk assessment
single cell
case control
electronic health record