Pterostilbene Alleviates Aβ1-42 -Induced Cognitive Dysfunction via Inhibition of Oxidative Stress by Activating Nrf2 Signaling Pathway.

Jikai XuJingyu LiuQing LiYan MiDi ZhouQingqi MengGang ChenLibin XuYue Hou

Published in: Molecular nutrition & food research (2020)

The present study reports that pterostilbene alleviated Aβ1-42 -induces cognitive dysfunction in mice. The mechanism of pterostilbene can be associated to the inhibition of oxidative stress through the Nrf2 signaling pathway.

Keyphrases

oxidative stress
signaling pathway
diabetic rats
induced apoptosis
pi k akt
dna damage
ischemia reperfusion injury
epithelial mesenchymal transition
high glucose
emergency department
mouse model
type diabetes
cell proliferation
drug induced
insulin resistance
adipose tissue
adverse drug
endoplasmic reticulum stress