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Der p 23-specific IgE response throughout childhood and its association with allergic disease: A birth cohort study.

Leandra ForchertEkaterina PotapovaValentina PanettaStephanie DramburgSerena PernaDaniela PosaYvonne Resch-MaratChristian LupinekAlexander RohrbachLinus B GrabenhenrichKatja IckeCarl-Peter BauerUte HoffmanJohannes ForsterFred ZeppAntje SchusterUlrich WahnThomas KeilSusanne LauSusanne VrtalaRudolph ValentaPaolo Maria Matricardi
Published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2022)
Der p 23 sensitisation peaks in late childhood and then decreases. It is preceded by early mite exposure and AD. Asthma and AR can occur in patients persistently sensitised to Der p 23 as the only mite allergen, suggesting the inclusion of molecular testing of Der p 23-sIgE for subjects with clinical suspicion of HDM allergy but without sIgE to other major D.pt. allergens.
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