A prospective observational study to evaluate a possible relationship between vitamin K antagonist therapy and risk of peripheral arterial disease in patients with type 2 diabetes.

Olivier BourronKamel MohammediJoe De KeizerFabrice SchneiderSamy HadjadjPierre-Jean Saulnier

Published in: Diabetes, obesity & metabolism (2024)

In this prospective study, we did not observe any excess risk of PAD requiring lower-limb revascularization in people with type 2 diabetes using VKAs. However, our data suggest a high risk of LLA in VKA users. Further studies are required to confirm this observation.

Keyphrases

lower limb
electronic health record
percutaneous coronary intervention
coronary artery bypass grafting
big data
case control
stem cells
machine learning
mesenchymal stem cells
coronary artery disease
acute coronary syndrome
bone marrow
chemotherapy induced