Improvement of gram-negative susceptibility to fluoroquinolones after implementation of a pre-authorization policy for fluoroquinolone use: A decade-long experience.
Rachael A LeeMorgan C ScullyBernard C CaminsRussell L GriffinDanielle F KunzStephen A MoserCraig J HoesleyTodd P McCartyPeter G PappasPublished in: Infection control and hospital epidemiology (2018)
A stewardship-driven FQ restriction program stopped overall declining FQ susceptibility rates for all species except E. coli. For 3 species (ie, Acinetobacter spp, E. cloacae, and P. aeruginosa), susceptibility rates improved after implementation, and this improvement has been sustained over a 10-year period.