Definitive radio(chemo)therapy versus upfront surgery in the treatment of HPV-related localized or locally advanced oropharyngeal squamous cell carcinoma.
Jérémy BaudeCaroline GuigouDavid ThibouwNoémie VulquinMireille FoliaGuillaume ConstantinJihane BoustaniChristian DuvillardSylvain LadoireGilles TrucAurélie BertautCédric ChevalierPublished in: PloS one (2024)
There was no significant difference in efficacy, physician-reported toxicity and overall patient-reported quality of life was found between non-minimally invasive surgery and radio±chemotherapy in the treatment of stage I-III HPV-OPSCC.
Keyphrases
- locally advanced
- squamous cell carcinoma
- rectal cancer
- patient reported
- neoadjuvant chemotherapy
- radiation therapy
- high grade
- minimally invasive
- emergency department
- oxidative stress
- combination therapy
- clinical trial
- photodynamic therapy
- coronary artery disease
- coronary artery bypass
- lymph node
- drug delivery
- bone marrow
- cancer therapy
- double blind