A novel sympathetic neuronal GABAergic signalling system regulates NE release to prevent ventricular arrhythmias after acute myocardial infarction.

Yugen ShiYan LiJie YinHesheng HuMei XueXiaolu LiWenjuan ChengYe WangXinran LiYu WangJiayu TanSuhua Yan

Published in: Acta physiologica (Oxford, England) (2019)

The GABAergic signalling system is functionally expressed in SCG sympathetic neurons, and activation of this system suppresses sympathetic activity, thereby facilitating cardiac protection and making it a potential target to alleviate VAs.

Keyphrases

acute myocardial infarction
left ventricular
heart failure
percutaneous coronary intervention
spinal cord
signaling pathway
catheter ablation
coronary artery disease
congenital heart disease
spinal cord injury
atrial fibrillation