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Synthetic antigenic determinants of clavulanic acid induce dendritic cell maturation and specific T cell proliferation in patients with immediate hypersensitivity reactions.

Rubén Fernández SantamariaGador BogasMaría Isabel MontañezAdriana Ariza VeguillasMaria SalasCéspedes José AntonioMarina LabellaJuan Luis ParisPérez-Sánchez NataliaEzequiel Pérez-InestrosaYolanda VidaTahia Diana FernandezCristobalina MayorgaTorres María José
Published in: Allergy (2022)
Th2 cells from AP. The combination of analogues from both ADs, significantly increased the sensitivity of DC maturation and T-cell proliferation compared to native CLV.
Keyphrases
  • cell proliferation
  • dendritic cells
  • cell cycle
  • regulatory t cells
  • pi k akt
  • immune response
  • transcription factor
  • molecular docking
  • drug induced
  • signaling pathway