[Comparison of two types of sorbents for solid-phase extraction of cannabimimetic MDMB(N)-073F metabolites from urine].
S S KataevOksana DvorskayaMariia GofenbergPublished in: Sudebno-meditsinskaia ekspertiza (2021)
The purpose of this work is to study the possibility of using cartridges with a mixed sorbent C8/SAX for the extraction of synthetic cannabimimetic metabolites MDMB (N)-073F from urine. It was used enzymatic hydrolysis of urine, solid phase extraction using cartridges C8/SAX and C8/SCX with mixed phase, derivatization and gas chromatography with a mass spectrometric detector. The results of the study allow us to recommend cartridges for solid-phase extraction with an anion-exchange phase (C8/SAX or SAX) when conducting a targeted study for the presence of cannabimimetics metabolites that have compounds with a carboxyl group as the main metabolites.
Keyphrases
- solid phase extraction
- gas chromatography
- high performance liquid chromatography
- liquid chromatography tandem mass spectrometry
- tandem mass spectrometry
- molecularly imprinted
- gas chromatography mass spectrometry
- simultaneous determination
- liquid chromatography
- ultra high performance liquid chromatography
- ms ms
- high resolution mass spectrometry
- magnetic resonance
- ionic liquid