Management of Covid Associated Mucormycosis of Mandible: A Mountain Beneath a Molehill-A Lesson Learnt.
Saubhik DasukilKiran Kumar BoyinaSaurav SarkarVinaykumar HallurAnindya NayakAbhijeet Kumar MishraK V AswathiChappity PreetamPradipta Kumar ParidaPublished in: Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India (2021)
The opportunistic infection of post-Covid associated mucormycosis has been reported globally; however, it has reached alarming proportions in India. Mucormycosis of the mandibular region is rare, and only a few cases have been reported to date. Covid associated mucormycosis has not been reported in the literature before, and we are the first to report them. We report two patients who presented with tooth loosening with pus discharge a few weeks following recovery from Covid infection. After tooth extraction adjacent necrotic bony specimen was sent for calcofluor potassium hydroxide mount, which was found positive for broad pauciseptate hyphae. Although CT scan imaging demonstrated the involvement of a mandible segment, we found a much more extensive involvement in both cases during resection. There was intramedullary spread of the mucormycosis throughout the inferior alveolar canal, with pus discharge and foul odor. The management of covid associated mandibular mucormycosis consists of surgical debridement with antifungal therapy and control of the underlying disease. It became challenging because the radiological extent of the disease was different from the definite clinical extension of the lesion found during surgery. The authors recommend surgeons adopt a flexible approach during surgery to plan resection depending on the clinical judgment and not rely entirely on CT scans. And the reconstruction of the mandible will follow as per the extent of excision.
Keyphrases
- coronavirus disease
- sars cov
- computed tomography
- minimally invasive
- dual energy
- coronary artery bypass
- contrast enhanced
- respiratory syndrome coronavirus
- systematic review
- image quality
- stem cells
- positron emission tomography
- magnetic resonance imaging
- mass spectrometry
- surgical site infection
- mesenchymal stem cells
- magnetic resonance
- quality improvement
- atrial fibrillation
- percutaneous coronary intervention
- smoking cessation
- gestational age