Targeted Proteomic Analysis of Patients with Ascending Thoracic Aortic Aneurysm.
Aphrodite DaskalopoulouSotiria G GiotakiKonstantina ToliAngeliki MiniaVaia PliakaLeonidas G AlexopoulosGerasimos DeftereosKonstantinos IliodromitisDimitrios DimitroulisGerasimos SiasosChristos VerikokosDimitrios IliopoulosPublished in: Biomedicines (2023)
CCL5, HBD1 and ICAM1 are very promising biomarkers with satisfying sensitivity and specificity that could be helpful in stratifying risk for the development of ATAA. These biomarkers may assist in the diagnosis and follow-up of patients at risk of developing ATAA. This retrospective study is very encouraging; however, further in-depth studies may be worthwhile to investigate the role of these biomarkers in the pathogenesis of ATAA.