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Shared genetic architecture highlights the bidirectional association between major depressive disorder and fracture risk.

Pianpian ZhaoZhimin YingChengda YuanHaisheng ZhangAo DongJianguo TaoXiangjiao YiMengyuan YangWen JinWeiliang TianDavid KarasikGeng TianHou-Feng Zheng
Published in: General psychiatry (2024)
) between the diseases suggest that modulating the endocannabinoid system could be a potential therapeutic strategy for both MDD and bone loss.
Keyphrases
  • major depressive disorder
  • bone loss
  • bipolar disorder
  • signaling pathway
  • genome wide
  • copy number
  • dna methylation