Mapping Human Fetal Brain Maturation In Vivo Using Quantitative MRI.

Victor U Schmidbauer Gregor O Dovjak Mehmet-Salih Yildirim Gudrun Mayr-Geisl Michael Weber Mariana C Diogo Gerlinde Maria Gruber Florian Prayer Ruxandra-Iulia Milos Marlene Stümpflen Barbara Ulm Julia Binder Dieter Bettelheim Herbert Kiss Daniela Prayer Gregor J Kasprian

Published in: AJNR. American journal of neuroradiology (2021)

Fetal motion limits the applicability of multidynamic multiecho-based postprocessing. However, SyMRI-generated image data of sufficient quality enable the qualitative assessment of maturity-related changes of the fetal brain. In addition, quantitative T2 relaxation time/T2 relaxation rate mapping characterizes myelin-related changes of the brain stem prenatally. This approach, if successful, opens novel possibilities for the evaluation of structural and biochemical aspects of fetal brain maturation.

Keyphrases

white matter
resting state
high resolution
functional connectivity
systematic review
machine learning
magnetic resonance
big data
contrast enhanced
brain injury
subarachnoid hemorrhage