FLAER-negative CD15+ neutrophils can be used for the simplified screening of suspected PNH cases.

Alexandra SemchenkovaSvetlana KashporTatiana VerzhbitskayaVyacheslav BorisovOlga IllarionovaLarisa FechinaAlexey MaschanGalina NovichkovaAlexander Popov

Published in: International journal of laboratory hematology (2020)

This simple two-color evaluation of FLAER-negative neutrophils is a highly effective screening test for PNH. Although this approach is not intended to replace the multicolor diagnostic procedure, it could minimize the number of patients requiring a conventional multicolor flow cytometric assay.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
pulmonary embolism
high throughput
minimally invasive
patient reported outcomes
patient reported