RNA sequencing of single allergen-specific memory B cells after grass pollen immunotherapy: Two unique cell fates and CD29 as a biomarker for treatment effect.
Craig I McKenzieNirupama P VaresePei Mun AuiSimone ReinwaldBruce D WinesPhilip Mark HogarthFrancis ThienMark HewJennifer M RollandRobyn Elizabeth O'HehirMenno C van ZelmPublished in: Allergy (2022)
A clinically successful 4 months course of SLIT for grass pollen allergy induces two transcriptionally unique Bmem fates. Associated changes in surface-expressed proteins on these Bmem subsets can be used as early biomarkers for treatment effects.
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