RNA sequencing of single allergen-specific memory B cells after grass pollen immunotherapy: Two unique cell fates and CD29 as a biomarker for treatment effect.

Craig I McKenzie Nirupama P Varese Pei Mun Aui Simone Reinwald Bruce D Wines Philip Mark Hogarth Francis Thien Mark Hew Jennifer M Rolland Robyn Elizabeth O'Hehir Menno C van Zelm

Published in: Allergy (2022)

A clinically successful 4 months course of SLIT for grass pollen allergy induces two transcriptionally unique Bmem fates. Associated changes in surface-expressed proteins on these Bmem subsets can be used as early biomarkers for treatment effects.

Keyphrases

stem cells
atopic dermatitis