Relationship between bile salts, bacterial translocation, and duodenal mucosal integrity in functional dyspepsia.
Dorien BeeckmansRicard FarréDanny RiethorstÅsa V KeitaPatrick AugustijnsJohan D SöderholmTim VanuytselHanne VanheelTack JanPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2020)
Patients with FD displayed decreased duodenal mucosal resistance associated with bile salts, however, not associated with bacterial passage in vitro. In addition, the hydrophilic bile salt glyco-ursodeoxycholic acid abolished differences in mucosal resistance and bacterial passage between patient and control group.