Mesentery AjFGF4-AjFGFR2-ERK pathway modulates intestinal regeneration via targeting cell cycle in echinoderms.

Chuili ZengMing GuoYangxi XiangMingshan SongKe XiaoChenghua Li

Published in: Cell proliferation (2022)

We provide the first functional evidence that AjFGF4-AjFGFR2-ERK-cell cycle axis mediated cell proliferation was the engine for mesentery-derived intestine regeneration in echinoderms.

Keyphrases

cell cycle
cell proliferation
stem cells
pi k akt
signaling pathway
wound healing
cancer therapy
drug delivery