Clinical Characteristics and Growth Hormone Treatment in Patients with Prader-Willi Syndrome

Aydilek Dagdeviren Cakir Firdevs Baş Onur Akın Zeynep Şiklar Mesut Dursun Merih Berberoğlu Asli Derya Kardelen Al Elvan Bayramoğlu Şükran Poyrazoğlu Hasan Murat Aydın Ayça Törel Ergür Ruhsar Damla Gökşen Şimşek Semih Bolu Zehra Aycan Beyhan Tüysüz Oya Ercan Saadet Olcay Evliyaoglu

Published in: Journal of clinical research in pediatric endocrinology (2021)

The most frequent complaints were hypotonia and feeding difficulty at first presentation. Obesity was the initial finding in 44.2%. GH treatment was started in less than half of the patients. While GH treatment significantly increased height SDS, BMI SDS remained unchanged, possibly due to the relatively older age at GH start.

Keyphrases

growth hormone
body mass index
type diabetes
metabolic syndrome
end stage renal disease
adipose tissue
newly diagnosed
prognostic factors
weight gain
patient reported