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Changes in mitochondrial distribution occur at the axon initial segment in association with neurodegeneration in Drosophila .

Andrew P K WodrichBrent T HarrisEdward Giniger
Published in: bioRxiv : the preprint server for biology (2024)
, mitochondria are excluded from the axon iniCal segment, a neuronal compartment that regulates neuron polarity and axon potenCals, and this paYern is disrupted in a model of neurodegeneraCon.
Keyphrases
  • optic nerve
  • oxidative stress
  • cell death
  • optical coherence tomography
  • endoplasmic reticulum
  • subarachnoid hemorrhage