A Preclinical Study of Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells for Treating Detrusor Underactivity by Chronic Bladder Ischemia.

Hwan Yeul YuJung Hyun ShinHongDuck YunChae-Min RyuSeungun LeeJinbeom HeoJisun LimJuhyun ParkKi-Sung HongHyung-Min ChungDong-Myung ShinMyung-Soo Choo

Published in: Stem cell reviews and reports (2021)

Single injection of M-MSCs directly into the bladder of a CBI-induced DUA rat model improved voiding profiles and repaired the bladder muscle atrophy in a dose-dependent manner.

Keyphrases

spinal cord injury
stem cells
endothelial cells
urinary tract
high glucose
mesenchymal stem cells
skeletal muscle
drug induced
cell therapy
ultrasound guided
induced pluripotent stem cells