Glioblastoma cells potentiate the induction of the Th1-like profile in phosphoantigen-stimulated γδ T lymphocytes.

David A RossoMicaela RosatoJuan IturrizagaNazareno GonzálezCarolina M ShiromizuIrene A KeitelmanJuan V CoronelFernando D GómezMaría M AmaralAlejandra T RabadanGabriela V SalamoneCarolina Cristina Jancic

Published in: Journal of neuro-oncology (2021)

GBM cells enhanced Th1-like profile differentiation in phosphoantigen-stimulated γδ T cells. Our results reinforce data that have demonstrated the implication of Vγ9Vδ2 T cells in the control of GBM, and this knowledge is fundamental to the development of immunotherapeutic protocols to treat GBM based on γδ T cells.

Keyphrases

induced apoptosis
cell cycle arrest
healthcare
endoplasmic reticulum stress
cell death
electronic health record
big data
machine learning
cell proliferation
deep learning