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History of consolidation is prognostic in acute myeloid leukemia patients undergoing allogeneic hematopoietic cell transplantation in minimal residual disease-negative first complete remission.

Armin RashidiMichael A LindenTodd E DeForErica WarlickNelli BejanyanSophia YoheDaniel J WeisdorfCelalettin Ustun
Published in: American journal of hematology (2017)
In AML patients undergoing allo-HCT in MRD-negative CR1, a history of prior consolidation was associated with favorable outcomes. If the path to pre-HCT MRD negativity includes consolidation, it may identify patients with improved prognosis following HCT in MRD-negative state. These results warrant validation in larger cohorts.
Keyphrases
  • patients undergoing
  • cell cycle arrest
  • stem cell transplantation
  • acute myeloid leukemia
  • cell death
  • systemic lupus erythematosus
  • high dose
  • signaling pathway
  • pi k akt