Comparing transfusion reaction rates for various plasma types: a systematic review and meta-analysis/regression.
Nicholas H SaadahFabienne M A van HoutMartin R SchipperusSaskia le CessieRutger A MiddelburgJohanna C Wiersum-OsseltonJohanna G van der BomPublished in: Transfusion (2017)
Meta-regression demonstrates that the rate of FNHTRs is lower for methylene blue-treated compared with FFP, and the rate of TRALI is lower for male-only than for mixed-sex FFP; whereas no significant differences are observed between plasma types for allergic reactions, TACO, or anaphylactic reactions. Reported transfusion reaction rates suffer from high heterogeneity.