Population-Specific Distribution of TPMT Deficiency Variants and Ancestry Proportions in Ecuadorian Ethnic Groups: Towards Personalized Medicine.

Jennifer Gallardo-CóndorPablo NaranjoSebastián AtarihuanaDayana CoelloPatricia Guevara-RamírezRodrigo Flores-EspinozaGerman Burgos Andrés López-Cortés Alejandro Cabrera-Andrade

Published in: Therapeutics and clinical risk management (2023)

The distribution of TPMT-deficient variants offers valuable insights into the populations under study, underscoring the necessity for genetic screening strategies to prevent thiopurine toxicity events among Latin American minority groups.

Keyphrases

copy number
genome wide
oxidative stress