HIV drug resistance patterns in pregnant women using next generation sequence in Mozambique.
María RupérezMarc Noguera-JulianRaquel GonzálezSonia MaculuveRocío BellidoAnifa ValaCristina RodríguezEsperança SeveneRoger ParedesClara MenéndezPublished in: PloS one (2018)
Even with ultrasensitive HIV-1 genotyping, less than 20% of women with detectable viremia at delivery had HIVDRM before initiating pMTCT or ART. This suggests that factors other than pre-existing resistance, such as lack of adherence or interruptions of the ANC chain, are also relevant to explain lack of virological suppression at the time of delivery in women receiving antiretrovirals drugs during pregnancy.
Keyphrases
- antiretroviral therapy
- hiv infected
- hiv positive
- pregnant women
- human immunodeficiency virus
- hiv infected patients
- hiv aids
- hiv testing
- hepatitis c virus
- men who have sex with men
- gold nanoparticles
- pregnancy outcomes
- genome wide
- high throughput
- gene expression
- quantum dots
- dna methylation
- south africa
- genetic diversity
- mass spectrometry
- drug induced