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Efficacy and Safety of Methylnaltrexone for the Treatment of Opioid-Induced Constipation: A Meta-analysis of Randomized Controlled Trials.

Ying-Ying ZhangRong ZhouWan-Jie Gu
Published in: Pain and therapy (2021)
Methylnaltrexone is an effective and safe drug for the treatment of OIC, but the safety of abdominal pain should be considered.
Keyphrases
  • abdominal pain
  • systematic review
  • oxidative stress
  • combination therapy
  • irritable bowel syndrome