Outcome of patients with newly diagnosed primary CNS lymphoma after high-dose methotrexate followed by consolidation whole-brain radiotherapy and cytarabine: an 8-year cohort study.
Pokpong PiriyakhuntornThanawat RattanathammetheeSasinee HantrakoolChatree Chai-AdisaksophaEkarat RattarittamrongAdisak TantiworawitLalita NorasetthadaPublished in: International journal of clinical oncology (2021)
High-dose methotrexate followed by consolidation whole-brain radiotherapy and cytarabine has acceptable efficacy, great tolerability, and low toxicity in newly diagnosed PCNSL patients.
Keyphrases
- high dose
- newly diagnosed
- stem cell transplantation
- low dose
- early stage
- white matter
- resting state
- radiation therapy
- locally advanced
- radiation induced
- end stage renal disease
- oxidative stress
- diffuse large b cell lymphoma
- ejection fraction
- open label
- acute myeloid leukemia
- blood brain barrier
- clinical trial
- functional connectivity
- cerebral ischemia
- squamous cell carcinoma
- multiple sclerosis
- peritoneal dialysis
- double blind
- placebo controlled