A 58-year-old man with B-cell chronic lymphocytic leukemia and multiple strokes.
Francesca MagrinelliSara MariottoGianpaolo NadaliGiuseppe TodeschiniMassimiliano LanzafameTiziana CavallaroSalvatore MonacoSergio FerrariPublished in: Brain pathology (Zurich, Switzerland) (2021)
A 58-year-old male with B-cell chronic lymphocytic leukemia presented with fever, chest pain, and acute-onset neurological deficits suggestive of multiple strokes (A). Brain autopsy revealed softening areas in the brain parenchyma (B, C) corresponding to extensive necrosis (D) caused by neuroinvasion by Aspergillus hyphae (E, F) necrosis (D) caused by neuroinvasion by Aspergillus hyphae (E, F).