Effects of statins and exercise on postprandial lipoproteins in metabolic syndrome vs metabolically healthy individuals.

Laura Alvarez-JimenezAlfonso Moreno-CabañasMiguel Ramirez-JimenezFelix Morales-PalomoJuan F OrtegaRicardo Mora-Rodriguez

Published in: British journal of clinical pharmacology (2020)

Hypercholesteraemic MetS individuals (compared to MetH controls) fail to show an effect of exercise on reducing PPTG. However, chronic statin medication blunts the elevations in triglyceride after a fat meal (i.e., incremental area under the curve of PPTG) reducing their cardiovascular risk associated with their atherogenic dyslipidaemia. Statin decreases PPTG by reducing the secretion or accelerating the catabolism of intestinal Apo B48.

Keyphrases

cardiovascular disease
metabolic syndrome
low density lipoprotein
high intensity
coronary artery disease
physical activity
adipose tissue
healthcare
resistance training
insulin resistance
blood glucose
emergency department
blood pressure
skeletal muscle
glycemic control