Combined Docetaxel/Pictilisib-Loaded mPEGylated Nanocarriers with Dual HER2 Targeting Antibodies for Synergistic Chemotherapy of Breast Cancer.
Wei-Jie ChengShyr-Yi LinKuo-Hsiang ChuangMichael ChenHsiu-O HoLing-Chun ChenChien-Ming HsiehMing-Thau SheuPublished in: International journal of nanomedicine (2022)
Non-covalent modification with dual distinct epitopes BsAbs on the nanocarriers loaded with dual chemodrugs at a synergistic ratio was expected to be a promising therapeutic platform to overcome the chemoresistance of various cancers and warrants further development for future therapy in the clinical.