Selective Imaging of Lung Macrophages Using [11C]PBR28-Based Positron Emission Tomography.

Delphine L ChenEugene AgapovKangyun WuJacquelyn T EngleKiran Kumar Solingapuram SaiElizabeth ArentsonKatherine J SpaydKirby T MorelandKelsey TothDerek E ByersRichard A PierceJeffrey J AtkinsonRichard LaforestAndrew E GelmanMichael J Holtzman

Published in: Molecular imaging and biology (2021)

PET imaging with [11C]PBR28 can specifically detect macrophages versus neutrophils during lung inflammation and may be a useful biomarker of macrophage accumulation in lung disease.

Keyphrases

pet imaging
positron emission tomography
computed tomography
oxidative stress
pet ct
adipose tissue
photodynamic therapy