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Calcium Phosphate Product Is Associated with Subclinical Carotid Atherosclerosis in Type 2 Diabetes.

Anna Ramírez-MorrosMinerva Granado-CasasNuria AlcubierreMontserrat Martinez-AlonsoJordi RealEsmeralda CastelblancoAureli EsquerdaGonzalo CaoEsther Rubinat ArnaldoMarta HernándezNúria AlonsoElvira FernándezEsmeralda Castelblanco
Published in: Journal of diabetes research (2017)
We found no association of 25OHD with the presence of SCA. However, calcium phosphate (CaP; mg2/dL2) product was positively associated with the presence of carotid plaques (ORadj = 1.078; 95% CI: 1.017-1.142). An inverse association was observed between higher levels of 25OHD (≥30 ng/mL versus <20 ng/mL concentrations) and common carotid intima-media thickness (cIMT; mm) (βadj ± SE = -0.055 ± 0.024). We conclude that the CaP product is independently associated with the presence of established subclinical carotid atherosclerosis in patients with T2DM.
Keyphrases
  • type diabetes
  • cardiovascular disease
  • glycemic control
  • optical coherence tomography
  • insulin resistance
  • adipose tissue
  • cardiovascular risk factors
  • skeletal muscle