Activation of small conductance Ca 2+ -activated K + channels suppresses Ca 2+ transient and action potential alternans in ventricular myocytes.

7.1 channel blocker HMR1556 (1 μM), subsequently were abolished by NS309 application in the presence of HMR1556. (b) Mean and individual cell CaT alternans ratios recorded from field stimulated ventricular myocytes in control, in the presence of HMR1556, followed by simultaneous application of HMR1556 and NS309. This article is protected by copyright. All rights reserved.