Developmental trajectory of transmission speed in the human brain.
Dorien van BlooijsMax A van den BoomJaap F van der AarGeertjan M HuiskampGiulio CastegnaroMatteo DemuruWillemiek J E M ZweiphenningPieter van EijsdenKai J MillerFrans S S LeijtenDora HermesPublished in: Nature neuroscience (2023)
The structure of the human connectome develops from childhood throughout adolescence to middle age, but how these structural changes affect the speed of neuronal signaling is not well described. In 74 subjects, we measured the latency of cortico-cortical evoked responses across association and U-fibers and calculated their corresponding transmission speeds. Decreases in conduction delays until at least 30 years show that the speed of neuronal communication develops well into adulthood.