Activated mast cells in skeletal muscle can be a potential mediator for cancer-associated cachexia.

D Brooke WidnerChun LiuQingxia ZhaoSarah SharpMatthew R EberSun H ParkD Clark FilesYusuke Shiozawa

Published in: Journal of cachexia, sarcopenia and muscle (2021)

Activated skeletal muscle-resident mast cells are enriched in cachectic muscles, suggesting skeletal-muscle resident mast cells may serve as a biomarker and mediator for cachexia development to improve patient diagnosis and prognosis.

Keyphrases

skeletal muscle
insulin resistance
patient safety
quality improvement
case report
metabolic syndrome
type diabetes
adipose tissue
climate change
human health