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Activated mast cells in skeletal muscle can be a potential mediator for cancer-associated cachexia.

D Brooke WidnerChun LiuQingxia ZhaoSarah SharpMatthew R EberSun H ParkD Clark FilesYusuke Shiozawa
Published in: Journal of cachexia, sarcopenia and muscle (2021)
Activated skeletal muscle-resident mast cells are enriched in cachectic muscles, suggesting skeletal-muscle resident mast cells may serve as a biomarker and mediator for cachexia development to improve patient diagnosis and prognosis.
Keyphrases
  • skeletal muscle
  • insulin resistance
  • patient safety
  • quality improvement
  • case report
  • metabolic syndrome
  • type diabetes
  • adipose tissue
  • climate change
  • human health